3c07: Difference between revisions

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[[Image:3c07.jpg|left|200px]]


{{Structure
==Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)==
|PDB= 3c07 |SIZE=350|CAPTION= <scene name='initialview01'>3c07</scene>, resolution 2.70&Aring;
<StructureSection load='3c07' size='340' side='right'caption='[[3c07]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+252'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+253'>AC2</scene> and <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+B+252'>AC3</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[3c07]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strco Strco]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ofl 2ofl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C07 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C07 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|GENE= SCO4850, SC5G8.18c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2 Bacteria])
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCO4850, SC5G8.18c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
|RELATEDENTRY=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c07 OCA], [https://pdbe.org/3c07 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c07 RCSB], [https://www.ebi.ac.uk/pdbsum/3c07 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c07 ProSAT], [https://www.topsan.org/Proteins/MCSG/3c07 TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c07 OCA], [http://www.ebi.ac.uk/pdbsum/3c07 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c07 RCSB]</span>
</table>
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/3c07_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
3C07 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. This structure supersedes the now removed PDB entry 2OFL. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C07 OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Bacteria]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c07 ConSurf].
[[Category: Edwards, A M.]]
<div style="clear:both"></div>
[[Category: Joachimiak, A.]]
__TOC__
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</StructureSection>
[[Category: Savchenko, A.]]
[[Category: Large Structures]]
[[Category: Tan, K.]]
[[Category: Strco]]
[[Category: Xu, X.]]
[[Category: Edwards, A M]]
[[Category: Zheng, H.]]
[[Category: Joachimiak, A]]
[[Category: apc6322]]
[[Category: Structural genomic]]
[[Category: dna-binding]]
[[Category: Savchenko, A]]
[[Category: mcsg]]
[[Category: Tan, K]]
[[Category: midwest center for structural genomic]]
[[Category: Xu, X]]
[[Category: protein structure initiative]]
[[Category: Zheng, H]]
[[Category: psi-2]]
[[Category: Apc6322]]
[[Category: streptomyces coelicolor a3(2)]]
[[Category: Dna-binding]]
[[Category: structural genomic]]
[[Category: Mcsg]]
[[Category: tetr]]
[[Category: PSI, Protein structure initiative]]
[[Category: transcription]]
[[Category: Tetr]]
[[Category: transcription regulation]]
[[Category: Transcription]]
[[Category: transcription regulator]]
[[Category: Transcription regulation]]
 
[[Category: Transcription regulator]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:30:00 2008''

Latest revision as of 07:38, 27 January 2022

Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2)

3c07, resolution 2.70Å

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