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==Structure of the Orthorhombic (Orthrhmb) Crystal Form of Human Apolipoprotein C1==
==Structure of the Orthorhombic (Orthrhmb) Crystal Form of Human Apolipoprotein C1==
<StructureSection load='6dz6' size='340' side='right' caption='[[6dz6]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='6dz6' size='340' side='right'caption='[[6dz6]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6dz6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DZ6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6dz6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DZ6 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dz6 OCA], [http://pdbe.org/6dz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dz6 RCSB], [http://www.ebi.ac.uk/pdbsum/6dz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dz6 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dz6 OCA], [https://pdbe.org/6dz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dz6 RCSB], [https://www.ebi.ac.uk/pdbsum/6dz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dz6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/APOC1_HUMAN APOC1_HUMAN]] Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.<ref>PMID:17339654</ref>
[https://www.uniprot.org/uniprot/APOC1_HUMAN APOC1_HUMAN] Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.<ref>PMID:17339654</ref>  
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: McPherson, A]]
[[Category: Large Structures]]
[[Category: Alpha helix]]
[[Category: McPherson A]]
[[Category: Lipid]]
[[Category: Lipid binding protein]]
[[Category: Lipoprotein particle]]

Latest revision as of 14:37, 13 March 2024

Structure of the Orthorhombic (Orthrhmb) Crystal Form of Human Apolipoprotein C1

6dz6, resolution 3.00Å

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