3mau: Difference between revisions

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==Crystal structure of StSPL in complex with phosphoethanolamine==
==Crystal structure of StSPL in complex with phosphoethanolamine==
<StructureSection load='3mau' size='340' side='right' caption='[[3mau]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='3mau' size='340' side='right'caption='[[3mau]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3mau]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_24528 Dsm 24528]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MAU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3mau]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Symbiobacterium_thermophilum Symbiobacterium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MAU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EXT:{5-HYDROXY-6-METHYL-4-[(E)-{[2-(PHOSPHONOOXY)ETHYL]IMINO}METHYL]PYRIDIN-3-YL}METHYL+DIHYDROGEN+PHOSPHATE'>EXT</scene>, <scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mad|3mad]], [[3maf|3maf]], [[3mc6|3mc6]], [[3mbb|3mbb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EXT:{5-HYDROXY-6-METHYL-4-[(E)-{[2-(PHOSPHONOOXY)ETHYL]IMINO}METHYL]PYRIDIN-3-YL}METHYL+DIHYDROGEN+PHOSPHATE'>EXT</scene>, <scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STH1274 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2734 DSM 24528])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mau OCA], [https://pdbe.org/3mau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mau RCSB], [https://www.ebi.ac.uk/pdbsum/3mau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mau ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sphinganine-1-phosphate_aldolase Sphinganine-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.27 4.1.2.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mau OCA], [http://pdbe.org/3mau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mau RCSB], [http://www.ebi.ac.uk/pdbsum/3mau PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mau ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q67PY4_SYMTH Q67PY4_SYMTH]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/3mau_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/3mau_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dsm 24528]]
[[Category: Large Structures]]
[[Category: Sphinganine-1-phosphate aldolase]]
[[Category: Symbiobacterium thermophilum]]
[[Category: Bourquin, F]]
[[Category: Bourquin F]]
[[Category: Capitani, G]]
[[Category: Capitani G]]
[[Category: Grutter, M G]]
[[Category: Grutter MG]]
[[Category: Carboxy-lyase activity]]
[[Category: Lyase]]
[[Category: Pyridoxyl phosphate]]

Latest revision as of 08:09, 4 March 2026

Crystal structure of StSPL in complex with phosphoethanolamine

3mau, resolution 2.90Å

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