3mex: Difference between revisions
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==Crystal structure of MexR in oxidized state== | ==Crystal structure of MexR in oxidized state== | ||
<StructureSection load='3mex' size='340' side='right' caption='[[3mex]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='3mex' size='340' side='right'caption='[[3mex]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3mex]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3mex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MEX FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mex OCA], [https://pdbe.org/3mex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mex RCSB], [https://www.ebi.ac.uk/pdbsum/3mex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mex ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MEXR_PSEAE MEXR_PSEAE] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/me/3mex_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/me/3mex_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Chen | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: He | [[Category: Chen H]] | ||
[[Category: Yang | [[Category: He C]] | ||
[[Category: Yi | [[Category: Yang C-G]] | ||
[[Category: Zhang | [[Category: Yi C]] | ||
[[Category: Zhang | [[Category: Zhang J]] | ||
[[Category: Zhang W]] | |||
Latest revision as of 09:25, 30 October 2024
Crystal structure of MexR in oxidized state
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