6gty: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==Crystal structure of the FimH lectin domain from E.coli K12 in complex with the dimannoside Man(alpha1-6)Man==
==Crystal structure of the FimH lectin domain from E.coli K12 in complex with the dimannoside Man(alpha1-6)Man==
<StructureSection load='6gty' size='340' side='right' caption='[[6gty]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='6gty' size='340' side='right'caption='[[6gty]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6gty]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GTY FirstGlance]. <br>
<table><tr><td colspan='2'>[[6gty]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GTY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gty OCA], [http://pdbe.org/6gty PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gty RCSB], [http://www.ebi.ac.uk/pdbsum/6gty PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gty ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gty OCA], [https://pdbe.org/6gty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gty RCSB], [https://www.ebi.ac.uk/pdbsum/6gty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gty ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.  
[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 19:
</div>
</div>
<div class="pdbe-citations 6gty" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6gty" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adhesin 3D structures|Adhesin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Canonica, F]]
[[Category: Escherichia coli K-12]]
[[Category: Ernst, B]]
[[Category: Large Structures]]
[[Category: Glockshuber, R]]
[[Category: Canonica F]]
[[Category: Jakob, R P]]
[[Category: Ernst B]]
[[Category: Luber, T]]
[[Category: Glockshuber R]]
[[Category: Maier, T]]
[[Category: Jakob RP]]
[[Category: Navarra, G]]
[[Category: Luber T]]
[[Category: Sauer, M M]]
[[Category: Maier T]]
[[Category: Unverzagt, C]]
[[Category: Navarra G]]
[[Category: Catch-bond]]
[[Category: Sauer MM]]
[[Category: Cell adhesion]]
[[Category: Unverzagt C]]
[[Category: Infection]]
[[Category: Lectin]]
[[Category: Mannose]]
[[Category: Type i pilus]]
[[Category: Upec]]
Retrieved from "https://proteopedia.org/6gty"