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==Crystal structure of QueE from Escherichia coli==
==Crystal structure of QueE from Escherichia coli==
<StructureSection load='6nhl' size='340' side='right' caption='[[6nhl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6nhl' size='340' side='right'caption='[[6nhl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6nhl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NHL FirstGlance]. <br>
<table><tr><td colspan='2'>[[6nhl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NHL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.101&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/7-carboxy-7-deazaguanine_synthase 7-carboxy-7-deazaguanine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.99.3 4.3.99.3] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nhl OCA], [http://pdbe.org/6nhl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nhl RCSB], [http://www.ebi.ac.uk/pdbsum/6nhl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nhl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nhl OCA], [https://pdbe.org/6nhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nhl RCSB], [https://www.ebi.ac.uk/pdbsum/6nhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nhl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/A0A0E1M5B1_ECOLX A0A0E1M5B1_ECOLX]] Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.[HAMAP-Rule:MF_00917]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 7-carboxy-7-deazaguanine synthase]]
[[Category: Escherichia coli K-12]]
[[Category: Bell, B N]]
[[Category: Large Structures]]
[[Category: Dowling, D P]]
[[Category: Bell BN]]
[[Category: Drennan, C L]]
[[Category: Dowling DP]]
[[Category: Grell, T A.J]]
[[Category: Drennan CL]]
[[Category: Nguyen, C]]
[[Category: Grell TAJ]]
[[Category: Adomet]]
[[Category: Nguyen C]]
[[Category: Adomet radical enzyme]]
[[Category: Adomet radical fold]]
[[Category: Iron-sulfur cluster]]
[[Category: Lyase]]
[[Category: Metalloprotein]]
[[Category: Sam radical fold]]
Retrieved from "https://proteopedia.org/6nhl"