6j81: Difference between revisions
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New page: '''Unreleased structure''' The entry 6j81 is ON HOLD until Paper Publication Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Koba... |
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==Crystal structure of CERT START domain in complex with compound E14== | |||
<StructureSection load='6j81' size='340' side='right'caption='[[6j81]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6j81]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J81 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J81 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B8X:2-[4-[4-propyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>B8X</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j81 OCA], [https://pdbe.org/6j81 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j81 RCSB], [https://www.ebi.ac.uk/pdbsum/6j81 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j81 ProSAT]</span></td></tr> | ||
[[Category: Hanada | </table> | ||
[[Category: | == Disease == | ||
[[Category: | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry. | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: Suzuki | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Egawa D]] | |||
[[Category: Hanada K]] | |||
[[Category: Hanzawa H]] | |||
[[Category: Kawasaki S]] | |||
[[Category: Kobayashi S]] | |||
[[Category: Kumagai K]] | |||
[[Category: Nakao N]] | |||
[[Category: Sakai S]] | |||
[[Category: Suzuki M]] | |||
[[Category: Ueno M]] | |||
Latest revision as of 10:37, 27 March 2024
Crystal structure of CERT START domain in complex with compound E14
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