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[[Image:8a3h.gif|left|200px]]


{{Structure
==Cellobiose-derived imidazole complex of the endoglucanase cel5A from Bacillus agaradhaerens at 0.97 A resolution==
|PDB= 8a3h |SIZE=350|CAPTION= <scene name='initialview01'>8a3h</scene>, resolution 0.97&Aring;
<StructureSection load='8a3h' size='340' side='right'caption='[[8a3h]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IDC:5-HYDROXYMETHYL-5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-6YL-7,8-DIOL-GLUCOPYRANOSIDE'>IDC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[8a3h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salipaludibacillus_agaradhaerens Salipaludibacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A3H FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.97&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IDC:5-HYDROXYMETHYL-5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-6YL-7,8-DIOL-GLUCOPYRANOSIDE'>IDC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a3h OCA], [https://pdbe.org/8a3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a3h RCSB], [https://www.ebi.ac.uk/pdbsum/8a3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a3h ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=8a3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a3h OCA], [http://www.ebi.ac.uk/pdbsum/8a3h PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=8a3h RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/GUN5_SALAG GUN5_SALAG]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/8a3h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=8a3h ConSurf].
<div style="clear:both"></div>


'''Cellobiose-derived imidazole complex of the endoglucanase cel5A from Bacillus agaradhaerens at 0.97 A resolution'''
==See Also==
 
*[[Glucanase 3D structures|Glucanase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
8A3H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A3H OCA].
[[Category: Large Structures]]
[[Category: Bacillus agaradhaerens]]
[[Category: Salipaludibacillus agaradhaerens]]
[[Category: Cellulase]]
[[Category: Davies GJ]]
[[Category: Single protein]]
[[Category: Pipelier M]]
[[Category: Davies, G J.]]
[[Category: Schulein M]]
[[Category: Pipelier, M.]]
[[Category: Varrot A]]
[[Category: Schulein, M.]]
[[Category: Vasella A]]
[[Category: Varrot, A.]]
[[Category: Vasella, A.]]
[[Category: cellulose degradation]]
[[Category: endoglucanase]]
[[Category: glycoside hydrolase family 5]]
[[Category: lateral protonation]]
[[Category: transition state analogue]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:44:53 2008''