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==Candida albicans Hsp90 nucleotide binding domain in complex with radicicol==
==Candida albicans Hsp90 nucleotide binding domain in complex with radicicol==
<StructureSection load='6cjl' size='340' side='right' caption='[[6cjl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='6cjl' size='340' side='right'caption='[[6cjl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6cjl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CJL FirstGlance]. <br>
<table><tr><td colspan='2'>[[6cjl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CJL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RDC:RADICICOL'>RDC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6972&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6cji|6cji]], [[6cjj|6cjj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RDC:RADICICOL'>RDC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjl OCA], [http://pdbe.org/6cjl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cjl RCSB], [http://www.ebi.ac.uk/pdbsum/6cjl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjl OCA], [https://pdbe.org/6cjl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cjl RCSB], [https://www.ebi.ac.uk/pdbsum/6cjl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HSP90_CANAL HSP90_CANAL]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).  
[https://www.uniprot.org/uniprot/HSP90_CANAL HSP90_CANAL] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
 
==See Also==
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Nation, C]]
[[Category: Candida albicans SC5314]]
[[Category: Pizarro, J C]]
[[Category: Large Structures]]
[[Category: Chaperone]]
[[Category: Nation C]]
[[Category: Hsp90. atpase]]
[[Category: Pizarro JC]]