6ggz: Difference between revisions

<StructureSection load='6ggz' size='340' side='right'caption='[[6ggz]]' scene=''>

<table><tr><td colspan='2'>[[6ggz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Androctonus_mauritanicus_mauritanicus Androctonus mauritanicus mauritanicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GGZ FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ggz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ggz OCA], [https://pdbe.org/6ggz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ggz RCSB], [https://www.ebi.ac.uk/pdbsum/6ggz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ggz ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/KA153_ANDMA KA153_ANDMA] Blocker of A-type voltage-gated potassium channels of striated neurons (PubMed:12473099). Has been shown to block ERG1/Kv11.1/KCNH2 potassium channels (IC(50)=7.9 uM) (PubMed:18687312). In adult rat brain, it binds to sites in the striatum, and cerebellum. It shares the same target in rat brain than AaTX1 (AC Q867F4) and BmTX3 (AC Q8I0L5).<ref>PMID:12473099</ref> <ref>PMID:18687312</ref>  

[[Category: Androctonus mauritanicus mauritanicus]]

[[Category: Large Structures]]

[[Category: Landon C]]

[[Category: Meudal H]]