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New page: left|200px {{Structure |PDB= 2ekn |SIZE=350|CAPTION= <scene name='initialview01'>2ekn</scene>, resolution 2.05Å |SITE= <scene name='pdbsite=AC1:Flc+Binding+Site+...
 
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[[Image:2ekn.jpg|left|200px]]


{{Structure
==Structure of PH1811 protein from Pyrococcus horikoshii==
|PDB= 2ekn |SIZE=350|CAPTION= <scene name='initialview01'>2ekn</scene>, resolution 2.05&Aring;
<StructureSection load='2ekn' size='340' side='right'caption='[[2ekn]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Flc+Binding+Site+For+Residue+A+585'>AC1</scene> and <scene name='pdbsite=AC2:Flc+Binding+Site+For+Residue+B+586'>AC2</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>
<table><tr><td colspan='2'>[[2ekn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EKN FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
|GENE= moaC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01419 MoaC_A]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ekn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ekn OCA], [https://pdbe.org/2ekn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ekn RCSB], [https://www.ebi.ac.uk/pdbsum/2ekn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ekn ProSAT], [https://www.topsan.org/Proteins/RSGI/2ekn TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ekn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ekn OCA], [http://www.ebi.ac.uk/pdbsum/2ekn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ekn RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/MOAC_PYRHO MOAC_PYRHO] Together with MoaA, is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity).
 
== Evolutionary Conservation ==
'''Structure of PH1811 protein from Pyrococcus horikoshii'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ek/2ekn_consurf.spt"</scriptWhenChecked>
2EKN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKN OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Pyrococcus horikoshii]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Lokanath, N K.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ekn ConSurf].
[[Category: Pampa, K J.]]
<div style="clear:both"></div>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
__TOC__
[[Category: biosynthetic protein]]
</StructureSection>
[[Category: molybdenum cofactor biosynthesis protein]]
[[Category: Large Structures]]
[[Category: national project on protein structural and functional analyse]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: nppsfa]]
[[Category: Lokanath NK]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Pampa KJ]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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Retrieved from "https://proteopedia.org/2ekn"