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New page: left|200px {{Structure |PDB= 2elm |SIZE=350|CAPTION= <scene name='initialview01'>2elm</scene> |SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+181'>AC1</s...
 
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[[Image:2elm.jpg|left|200px]]


{{Structure
==Solution structure of the 10th C2H2 zinc finger of human Zinc finger protein 406==
|PDB= 2elm |SIZE=350|CAPTION= <scene name='initialview01'>2elm</scene>
<StructureSection load='2elm' size='340' side='right'caption='[[2elm]]' scene=''>
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+181'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2elm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELM FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= ZFAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elm OCA], [https://pdbe.org/2elm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elm RCSB], [https://www.ebi.ac.uk/pdbsum/2elm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elm ProSAT], [https://www.topsan.org/Proteins/RSGI/2elm TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2elm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elm OCA], [http://www.ebi.ac.uk/pdbsum/2elm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2elm RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
 
__TOC__
'''Solution structure of the 10th C2H2 zinc finger of human Zinc finger protein 406'''
</StructureSection>
 
 
==Disease==
Known disease associated with this structure: Autoimmune thyroid disease, susceptibility to, 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=610931 610931]]
 
==About this Structure==
2ELM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELM OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Harada, T.]]
[[Category: Harada T]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tanaka A]]
[[Category: Tanaka, A.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Umehara T]]
[[Category: Umehara, T.]]
[[Category: Watanabe S]]
[[Category: Watanabe, S.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoneyama M]]
[[Category: Yoneyama, M.]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription]]
[[Category: zfat zinc finger 1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr  2 11:56:36 2008''
Retrieved from "https://proteopedia.org/2elm"