2elt: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
New page: left|200px {{Structure |PDB= 2elt |SIZE=350|CAPTION= <scene name='initialview01'>2elt</scene> |SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+181'>AC1</s...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2elt.jpg|left|200px]]


{{Structure
==Solution structure of the 3rd C2H2 zinc finger of human Zinc finger protein 406==
|PDB= 2elt |SIZE=350|CAPTION= <scene name='initialview01'>2elt</scene>
<StructureSection load='2elt' size='340' side='right'caption='[[2elt]]' scene=''>
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+181'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2elt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELT FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= ZFAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elt OCA], [https://pdbe.org/2elt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elt RCSB], [https://www.ebi.ac.uk/pdbsum/2elt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elt ProSAT], [https://www.topsan.org/Proteins/RSGI/2elt TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2elt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elt OCA], [http://www.ebi.ac.uk/pdbsum/2elt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2elt RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
 
== Evolutionary Conservation ==
'''Solution structure of the 3rd C2H2 zinc finger of human Zinc finger protein 406'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==Disease==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/2elt_consurf.spt"</scriptWhenChecked>
Known disease associated with this structure: Autoimmune thyroid disease, susceptibility to, 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=610931 610931]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2ELT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELT OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2elt ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Harada, T.]]
[[Category: Harada T]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tanaka A]]
[[Category: Tanaka, A.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Umehara T]]
[[Category: Umehara, T.]]
[[Category: Watanabe S]]
[[Category: Watanabe, S.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoneyama M]]
[[Category: Yoneyama, M.]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription]]
[[Category: zfat zinc finger 1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr  2 11:56:49 2008''

Latest revision as of 18:51, 29 May 2024

Solution structure of the 3rd C2H2 zinc finger of human Zinc finger protein 406

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=2elt&oldid=4173052"