6ji6: Difference between revisions
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New page: '''Unreleased structure''' The entry 6ji6 is ON HOLD Authors: Okajima, T., Arai, R. Description: Crystal structure of glutathione S-transferase complexed and modified with glutathione ... |
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==Crystal structure of glutathione S-transferase complexed and modified with glutathione== | |||
<StructureSection load='6ji6' size='340' side='right'caption='[[6ji6]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ji6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_japonicum Schistosoma japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JI6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ji6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ji6 OCA], [https://pdbe.org/6ji6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ji6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ji6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ji6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GST26_SCHJA GST26_SCHJA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. | |||
==See Also== | |||
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Arai | [[Category: Large Structures]] | ||
[[Category: Okajima | [[Category: Schistosoma japonicum]] | ||
[[Category: Arai R]] | |||
[[Category: Okajima T]] | |||
