2o12: Difference between revisions

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[[Image:2o12.jpg|left|200px]]


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==Mycobacterium tuberculosis Chorismate synthase in complex with FMN==
The line below this paragraph, containing "STRUCTURE_2o12", creates the "Structure Box" on the page.
<StructureSection load='2o12' size='340' side='right'caption='[[2o12]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2o12]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O12 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_2o12|  PDB=2o12  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o12 OCA], [https://pdbe.org/2o12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o12 RCSB], [https://www.ebi.ac.uk/pdbsum/2o12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o12 ProSAT]</span></td></tr>
 
</table>
'''Mycobacterium tuberculosis Chorismate synthase in complex with FMN'''
== Function ==
 
[https://www.uniprot.org/uniprot/AROC_MYCTU AROC_MYCTU]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2O12 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O12 OCA].  
Check<jmol>
[[Category: Chorismate synthase]]
  <jmolCheckbox>
[[Category: Mycobacterium tuberculosis]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o1/2o12_consurf.spt"</scriptWhenChecked>
[[Category: Single protein]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Bartunik, H D.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Bruning, M.]]
  </jmolCheckbox>
[[Category: TBSGC, TB Structural Genomics Consortium.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o12 ConSurf].
[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
<div style="clear:both"></div>
[[Category: Chorismate synthase]]
__TOC__
[[Category: Lyase]]
</StructureSection>
[[Category: M. tuberculosis]]
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis structural proteomics project]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Shikimate pathway]]
[[Category: Bartunik HD]]
[[Category: Structural genomic]]
[[Category: Bruning M]]
[[Category: Tb structural genomics consortium]]
[[Category: Tbsgc]]
[[Category: Xmtb]]