Aminotransferase 3D structures: Difference between revisions

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*Histidinol-phosphate aminotransferase
*Histidinol-phosphate aminotransferase


**[[8bj4]] – bmHPA – barrel medic <br />
**[[8bj3]] – bmHPA + PLP <br />
**[[8bj1]], [[8bj2]] – bmHPA + PLP derivative<br />
**[[1gew]], [[1iji]] – EcHPA + PLP – ''Escherichia coli'' <br />
**[[1gew]], [[1iji]] – EcHPA + PLP – ''Escherichia coli'' <br />
**[[1gey]], [[1fg7]] – EcHPA + PLP derivative <br />
**[[1gey]], [[1fg7]] – EcHPA + PLP derivative <br />
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**[[1uu2]], [[2f8j]] – TmHPA + PLP derivative <br />
**[[1uu2]], [[2f8j]] – TmHPA + PLP derivative <br />
**[[3cq4]] – CgHPA – ''Corynebacterium glutamicum''<br />
**[[3cq4]] – CgHPA – ''Corynebacterium glutamicum''<br />
**[[8ht4]] – CgHPA + PLP <br />
**[[3cq5]], [[3cq6]] – CgHPA + PLP derivative <br />
**[[3cq5]], [[3cq6]] – CgHPA + PLP derivative <br />
**[[3ffh]] – HPA – ''Listeria innocua''<br />
**[[3ffh]] – HPA – ''Listeria innocua''<br />
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**[[4rae]] – MtHPA – ''Mycobacterium tuberculosis''<br />
**[[4rae]] – MtHPA – ''Mycobacterium tuberculosis''<br />
**[[4r8d]], [[5c6u]], [[5yhv]] – MtHPA + PLP <br />
**[[4r8d]], [[5c6u]], [[5yhv]] – MtHPA + PLP <br />
**[[7szp]] – KpHPA + PLP – ''Klebsiella pneumoniae''<br />


*Ornithine aminotransferase
*Ornithine aminotransferase


**[[1oat]] – hOA + PLP – human <br />
**[[1oat]], [[7ta1]] – hOA + PLP – human <br />
**[[1gbn]], [[2can]] – hOA + PLP + inhibitor <br />
**[[1gbn]], [[2can]], [[5vwo]], [[6oia]], [[6v8c]], [[6v8d]], [[7lnm]], [[7lom]], [[7lon]], [[7ted]], [[7tev]], [[7tfp]], [[8v9m]] – hOA + PLP + inhibitor <br />
**[[2oat]] – hOA + PLP derivative <br />
**[[2oat]] – hOA + PLP derivative <br />
**[[2byj]], [[2byl]] – hOA (mutant) + PLP  <br />
**[[2byj]], [[2byl]] – hOA (mutant) + PLP  <br />
**[[7jx9]] – hOA + intermediate + inhibitor <br />
**[[7ta0]] – hOA + aminovaleric acid<br />
**[[5eav]] – TgOA – ''Toxoplasma gondii'' <br />
**[[5eav]] – TgOA – ''Toxoplasma gondii'' <br />
**[[5eqc]], [[4zwm]] – TgOA + PLP <br />
**[[5eqc]], [[4zwm]] – TgOA + PLP <br />
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**[[3nx3]] – CjACOAT – ''Campylobacter jejuni'' <br />
**[[3nx3]] – CjACOAT – ''Campylobacter jejuni'' <br />
**[[5viu]] – ACOAT – ''Elizabethkingia anophelis'' <br />
**[[5viu]] – ACOAT – ''Elizabethkingia anophelis'' <br />
**[[6w7x]] – ACOAT (mutant) – ''Stenotrophomonas maltophila'' <br />
**[[4jev]] – StACOAT + PLP derivative – ''Salmonella typhimurium'' <br />
**[[4jev]] – StACOAT + PLP derivative – ''Salmonella typhimurium'' <br />
**[[4jey]] – StACOAT (mutant) + PLP <br />
**[[4jey]] – StACOAT (mutant) + PLP <br />
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*[[Phosphoserine aminotransferase]]
*[[Phosphoserine aminotransferase]]


*Alanine glyoxylate aminotransferase
*Alanine glyoxylate aminotransferase or serine-pyruvate aminotransferase or 3-hydroxykynurenine transaminase


**[[1h0c]], [[2yob]], [[5f9s]], [[5og0]] – hAGA + PLP  <br />
**[[1h0c]], [[2yob]], [[5f9s]], [[5og0]], [[6rv1]] – hAGA + PLP  <br />
**[[4cbr]], [[4cbs]], [[5ofy]], [[5luc]] – hAGA (mutant) + PLP  <br />
**[[4cbr]], [[4cbs]], [[5ofy]], [[5luc]] – hAGA (mutant) + PLP  <br />
**[[1j04]], [[5hhy]] – hAGA + PLP derivative <br />
**[[1j04]], [[5hhy]], [[6rv0]] – hAGA + PLP derivative <br />
**[[4i8a]] – hAGA (mutant) + PLP derivative <br />
**[[4i8a]] – hAGA (mutant) + PLP derivative <br />
**[[3r9a]] – hAGA + PLP derivative + peroxisomal targeting signal receptor<br />
**[[3r9a]] – hAGA + PLP derivative + peroxisomal targeting signal receptor<br />
**[[4kxk]], [[4kyo]] – hAGA (mutant) + peroxisomal targeting signal receptor<br />
**[[4kxk]], [[4kyo]] – hAGA (mutant) + peroxisomal targeting signal receptor<br />
**[[1vjo]] – AGA + PLP - Nostoc <br />
**[[6mfb]] – AaAGA + PLP – ''Aedes aegypti''<br />
**[[2huf]] – AaAGA + PLP derivative – ''Aedes aegypti''<br />
**[[2huf]] – AaAGA + PLP derivative <br />
**[[2hui]] – AaAGA + PLP derivative + glyoxylate<br />
**[[2hui]] – AaAGA + PLP derivative + glyoxylate<br />
**[[2huu]] – AaAGA + PLP derivative + alanine<br />
**[[2huu]] – AaAGA + PLP derivative + alanine<br />
**[[6pk3]] – AtAGA + PLP – ''Arabidopsis thaliana'' <br />
**[[6pk1]] – AtAGA + PLP + pyruvate <br />
**[[1vjo]] – AGA + PLP - Nostoc <br />


*D-amino acid aminotransferase
*D-amino acid aminotransferase
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**[[4m0j]] - BtAAT – ''Burkholderia thailandensis''<br />
**[[4m0j]] - BtAAT – ''Burkholderia thailandensis''<br />
**[[4tm5]] - BtAAT + PLP <br />
**[[4tm5]] - BtAAT + PLP <br />
**[[8ayk]], [[8onm]] - AcAAT + PLP derivative – ''Aminobacterium colombiense''<br />
**[[8ahr]] - AcAAT + PLP <br />
**[[8onj]], [[8onl]] - AcAAT (mutant) + PLP <br />
**[[8ayj]] - AcAAT + PLP + aminooxypropionic acid<br />
**[[8onn]] - AcAAT (mutant) + PLP + aminooxypropionic acid<br />
**[[8aie]] - AcAAT + PLP derivative + cyclo-Ser<br />


*Branched chain amino acid aminotransferase
*Branched chain amino acid aminotransferase


**[[1ekf]], [[1ekp]], [[1ekv]] – hBCAT + PLP  <br />
**[[1ekf]], [[1ekp]], [[1ekv]] – hBCAT + PLP  <br />
**[[2hdk]], [[2hgw]], [[2hgx]], [[2hhf]], [[5mpr]] – hBCAT (mutant) + PLP  <br />
**[[2hdk]], [[2hgw]], [[2hgx]], [[2hhf]], [[5mpr]], [[6prx]] – hBCAT (mutant) + PLP  <br />
**[[1kt8]], [[1kta]] – hBCAT + PLP derivative <br />
**[[1kt8]], [[1kta]] – hBCAT + PLP derivative <br />
**[[2alh]], [[5bwr]], [[5bwt]], [[5bwu]], [[5bwv]], [[5bwx]], [[5bww]], [[5cr5]] – hBCAT + PLP + inhibitor <br />
**[[2alh]], [[5bwr]], [[5bwt]], [[5bwu]], [[5bwv]], [[5bwx]], [[5bww]], [[5cr5]] – hBCAT + PLP + inhibitor <br />
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**[[5cm0]] – GaBCAT + PLP – ''Geoglobus acetivorans'' <br />
**[[5cm0]] – GaBCAT + PLP – ''Geoglobus acetivorans'' <br />
**[[5e25]] – GaBCAT + PLP + ketoglutarate  <br />
**[[5e25]] – GaBCAT + PLP + ketoglutarate  <br />
**[[5ce8]] – BCAT + PLP – ''Thermoproteus uzoniensis'' <br />
**[[5ce8]] – TuBCAT + PLP – ''Thermoproteus uzoniensis'' <br />
**[[6thq]] – TuBCAT + PLP + norvaline<br />
**[[5u3f]] – MtBCAT + cycloserine <br />
**[[5u3f]] – MtBCAT + cycloserine <br />
**[[6nst]] - BCAT – ''Pseudomonas aeruginosa''<br />
**[[6nst]] - PaBCAT (mutant) – ''Pseudomonas aeruginosa''<br />
**[[6jif]] – PaBCAT + PLP  <br />
**[[6gkr]] – TteBCAT + PLP – ''Thermobaculum terrenum'' <br />
**[[6gkr]] – TteBCAT + PLP – ''Thermobaculum terrenum'' <br />
**[[7nea]] – TtBCAT (mutant) + PLP  <br />
**[[6q8e]] – TteBCAT + PLP derivative  <br />
**[[6q8e]] – TteBCAT + PLP derivative  <br />
**[[6h65]] – TteBCAT + PLP – ''Haliangium ochraceum'' <br />
**[[6h65]] – TteBCAT + PLP – ''Haliangium ochraceum'' <br />
**[[4whx]] – BCAT + PLP – ''Burkholderia pseudomallei'' <br />
**[[4whx]] – BpBCAT + PLP – ''Burkholderia pseudomallei'' <br />
**[[7lv7]] – BCAT – ''Giardia lamblia'' <br />
**[[7p3t]] – BCAT + PLP – ''Luminiphilus syltensis''<br />
**[[8ioz]] – MvBCAT – ''Mycobacterium vanbaalenii'' <br />
**[[8ivp]] – MvBCAT + PLP derivative <br />
**[[8isc]] – MvBCAT (mutant) + PLP derivative <br />
**[[8pnw]], [[8pny]] – BCAT + PLP – ''Blastococcus saxobsidens''<br />
 


*Aromatic amino acid aminotransferase
*Aromatic amino acid aminotransferase
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*Tryptophan aminotransferase
*Tryptophan aminotransferase


**[[3bwn]], [[3bwo]] – TRYAT + PLP derivative – ''Arabidopsis thaliana'' <br />
**[[3bwn]], [[3bwo]] – AtTRYAT + PLP derivative <br />


*Beta-phenylalanine aminotransferase
*Beta-phenylalanine aminotransferase
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**[[2jjh]] – MtLYSAT (mutant) + PLP + oxoglutarate<br />
**[[2jjh]] – MtLYSAT (mutant) + PLP + oxoglutarate<br />


*Gamma-aminobutyrate aminotransferase
*Gamma-aminobutyrate aminotransferase or 4-aminobutyrate aminotransferase


**[[1sf2]] – EcGABA + PLP  <br />
**[[4zsy]], [[4zsw]], [[4y0i]], [[4y0h]], [[4y0d]], [[6b6g]] – GABA + inactivator - pig <br />
**[[1sf2]], [[7jh3]] – EcGABA + PLP  <br />
**[[1sff]] – EcGABA + PLP derivative <br />
**[[1sff]] – EcGABA + PLP derivative <br />
**[[1szk]], [[1szs]], [[1szu]] – EcGABA (mutant) + PLP derivative <br />
**[[1szk]], [[1szs]], [[1szu]] – EcGABA (mutant) + PLP derivative <br />
**[[3r4t]] – GABA + PLP derivative – ''Mycobacterium marinum''<br />
**[[3r4t]] – GABA + PLP derivative – ''Mycobacterium marinum''<br />
**[[4ffc]] – GABA + PLP derivative – ''Mycobacterium abscessus''<br />
**[[4ffc]] – GABA + PLP derivative – ''Mycobacterium abscessus''<br />
**[[4zsy]], [[4zsw]], [[4y0i]], [[4y0h]], [[4y0d]], [[6b6g]] – GABA + inactivator - pig <br />
**[[6wj8]] – GABA + PLP derivative – ''Klebsiella pneumoniae''<br />


*ArnB aminotransferase
*ArnB aminotransferase
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**[[3nyt]] - PaWbpE (mutant) + PLP derivative<br />
**[[3nyt]] - PaWbpE (mutant) + PLP derivative<br />


*Alpha-aminoadipate aminotransferase
*Alpha-aminoadipate aminotransferase or kynurenine/alpha-aminoadipate aminotransferase


**[[6t8p]], [[6t8q]] - hAADAT + PLP derivative + inhibitor <br />
**[[4je5]] - AADAT + PLP derivative + PLP - yeast<br />
**[[2egy]], [[5eun]] - TtAADAT + PLP <br />
**[[2egy]], [[5eun]] - TtAADAT + PLP <br />
**[[3cbf]], [[2zyj]] - TtAADAT + PLP derivative<br />
**[[3cbf]], [[2zyj]] - TtAADAT + PLP derivative<br />
**[[2zp7]], [[2z1y]] - TtAADAT + PLP + leucine<br />
**[[2zp7]], [[2z1y]] - TtAADAT + PLP + leucine<br />
**[[4je5]] - AADAT + PLP derivative + PLP - yeast<br />


*Broad specificity aminotransferase
*Broad specificity aminotransferase
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*Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
*Adenosylmethionine-8-amino-7-oxononanoate aminotransferase


**[[6ge8]] - MtDAPA <br />
**[[4w1x]], [[4w1w]], [[4w1v]], [[4xjl]], [[4xjm]], [[4xjo]], [[4xjp]], [[4wya]], [[4wyc]], [[4wyd]], [[4wye]], [[4wyf]], [[4wyg]], [[4xew]] - MtDAPA + PLP  + inhibitor<br />
**[[4w1x]], [[4w1w]], [[4w1v]], [[4xjl]], [[4xjm]], [[4xjo]], [[4xjp]], [[4wya]], [[4wyc]], [[4wyd]], [[4wye]], [[4wyf]], [[4wyg]], [[4xew]] - MtDAPA + PLP  + inhibitor<br />
**[[4mqr]], [[4mqq]], [[4mqp]] - MtDAPA + inhibitor<br />
**[[4mqr]], [[4mqq]], [[4mqp]] - MtDAPA + inhibitor<br />
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**[[4uoy]] - EcPAT + PLP <br />
**[[4uoy]] - EcPAT + PLP <br />
**[[4uox]] - EcPAT + PLP + putrescine<br />
**[[4uox]] - EcPAT + PLP + putrescine<br />
**[[6gwi]] - PAT + PLP – ''Halomonas elongata''<br />


*Omega amino acid-pyruvate aminotransferase
*Omega amino acid-pyruvate aminotransferase
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**[[4uho]], [[4uhn]], [[4uhm]] - PaOAAT + PLP <br />
**[[4uho]], [[4uhn]], [[4uhm]] - PaOAAT + PLP <br />


*C-6’ aminotransferase
*C-6’ aminotransferase or GenB


**[[6cbo]] - MeAT – ''Micromonospora echinospora'' <br />
**[[6cbo]] – MeGenB1 – ''Micromonospora echinospora'' <br />
**[[5z83]] – MeAT + PLP  <br />
**[[5z83]] – MeGenB1 + PLP  <br />
**[[5z8a]] – MeAT + PLP + JI-20A <br />
**[[5z8a]] – MeGenB1 + PLP + JI-20A <br />
**[[5z8k]] – MeAT + PLP + neomycin <br />
**[[5z8k]] – MeGenB1 + PLP + neomycin <br />
**[[7lm0]] – MeGenB3 + PLP  <br />
**[[7lle]] – MeGenB4 + PLP  <br />
**[[7lld]] – MeGenB4 + PLP-sisomicin  <br />


*Kynurenine aminotransferase
*Kynurenine aminotransferase
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**[[6erk]] – DPAAT + PLP – ''Psychrobacter cryohalolentis'' <br />
**[[6erk]] – DPAAT + PLP – ''Psychrobacter cryohalolentis'' <br />
**[[6ed7]] – EcDPAAT + PLP + inhibitor<br />


*D-phenylglycine aminotransferase
*D-phenylglycine aminotransferase


**[[6dvs]] – DPGAT – ''Pseudomonas stutzeri'' <br />
**[[6dvs]] – PsDPGAT – ''Pseudomonas stutzeri'' <br />
**[[6g1f]] – PsDPGAT + PLP derivative<br />
 
*Aminopentol aminotransferase
 
**[[6hbs]] – SmAPAT + PLP – ''Sphingopykis macrogoltabida'' <br />
**[[6hbv]] – SmAPAT + PLP + PLP derivative<br />
 
*Taurine:2-oxoglutamate aminotransferase
 
**[[6jix]] – TOGAT + PLP + Glu – ''Bifidobacterium kashiwanohense'' <br />
 
*Diaminopimelate aminotransferase
 
**[[6oxm]] – DPAT – ''Verrucomicrobium spinosum''<br />
 
*Glutamine-fructose-6-phosphate aminotransferase
 
**[[6r4f]] – hGFPAT + G6P<br />
**[[6r4g]] – hGFPAT + G6P + UDP-GlcNAc<br />
**[[6svp]] – hGFPAT + Glu + G6P + UDP-GlcNAc<br />
**[[6r4j]] – hGFPAT (mutant) + Glu + G6P + UDP-GlcNAc<br />
**[[6svm]] – hGFPAT + Glu + G6P + UDP-GlcNAc + inhibitor<br />
**[[6r4h]], [[6svq]] – hGFPAT + Glu + G6P<br />
**[[6svo]] – hGFPAT + Glu + G6P derivative<br />
**[[6r4i]] – hGFPAT (mutant) + Glu + G6P<br />
**[[6r4e]], [[6zmk]] – hGFPAT + PLP + Glu + G6P<br />
 
*Aminotransferase
 
**[[7vrx]] – AT + PLP derivative – tomato<br />
**[[6l1l]] – BsAT + PLP – ''Bacillus subtilis''<br />
**[[6l1n]] – BsAT + PLP + Gly<br />
**[[6l1o]] – BsAT + PLP + PLP derivative + Tyr<br />
**[[6qp1]] – ShAT + inhibitor – ''Staphylococcus hominis''<br />
**[[6qp2]] – ShAT + PLP + polyHis<br />
**[[6t3v]] – PsAT + PLP + substrate analog<br />
**[[6u7a]] – MtAT + PLP + PLP derivative + kynurenine<br />
 
*Aminotransferase class I/II or PLP-dependent aminotransferase
 
**[[3op7]], [[3p6k]] – AT + PLP derivative – ''Streptococcus suis''<br />
**[[8tn2]] – ShAT + PLP – ''Streptomyces hygroscopicus''<br />
**[[8tn3]] – ShAT + PLP derivative <br />
**[[7pq9]] – AcAT – ''Alkalihalobacillus clausii'' <br />
**[[7zla]], [[7zn5]], [[7zpa]], [[7zth]] – AcAT + DNA – Cryo EM<br />
**[[7kz3]], [[7kz6]] – BcAT + PLP derivative – ''Bacillus cereus''<br />
**[[7kz5]] – BcAT + PLP derivative + kanosamine-6-phosphate<br />
**[[7kzd]] – BcAT + PLP derivative + glutarate<br />


*Aminotransferase class II
*Aminotransferase class II
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**[[5m49]] – RfAT3 + PLP + azepan derivative<br />
**[[5m49]] – RfAT3 + PLP + azepan derivative<br />
**[[5m4b]], [[5m4d]] – RfAT3 (mutant) + azepan derivative<br />
**[[5m4b]], [[5m4d]] – RfAT3 (mutant) + azepan derivative<br />
**[[5d95]] – AT3 + PLP derivative – ''Sphaerobacter thermophilus''<br />
**[[6k8h]] – AT3 + PLP derivative – ''Sphaerobacter thermophilus''<br />
**[[6io1]] – AT3 + PLP derivative – ''Thermomicrobium roseum''<br />


*Aminotransferase class IV
*Aminotransferase class IV


**[[4tvi]] – AT4 + PLP derivative – ''Brucella abortus''<br />
**[[4tvi]] – AT4 + PLP derivative – ''Brucella abortus''<br />
**[[7z79]] – VpAT4 + PLP <br />
**[[7p8o]], [[8yrt]], [[8yru]] – HhAT4 – ''Haliscomenobacter hydrossis'' <br />
**[[7p7x]] – HhAT4 + PLP <br />
**[[8raf]] – HhAT4 (mutant) + PLP <br />
**[[8ahu]] – HhAT4 + cyclo-Ser <br />
**[[8yrv]] – HhAT4 + aminooxypropionic acid<br />
**[[8rai]] – HhAT4 + phenylhydrazine<br />
**[[8ahu]] – AT4 + cyclo-Ser – ''Haliscomenobacter hydrossis'' <br />
*Aminotransferase class V


**[[5f8v]] – AT5 + PLP derivative – ''Trichomonas vaginalis''<br />
**[[9aza]] – AT5 + PLP – ''Penicillium expansum''<br />


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