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<StructureSection load='5ipf' size='340' side='right'caption='[[5ipf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5ipf' size='340' side='right'caption='[[5ipf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ipf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IPF FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ipf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IPF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HGPRT, Smp_103560 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Blood fluke])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ipf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipf OCA], [https://pdbe.org/5ipf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ipf RCSB], [https://www.ebi.ac.uk/pdbsum/5ipf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ipf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipf OCA], [http://pdbe.org/5ipf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipf RCSB], [http://www.ebi.ac.uk/pdbsum/5ipf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPRT_SCHMA HPRT_SCHMA] Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ipf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ipf" style="background-color:#fffaf0;"></div>
==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Blood fluke]]
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bird, L E]]
[[Category: Schistosoma mansoni]]
[[Category: Brandao-Neto, J]]
[[Category: Bird LE]]
[[Category: DeMarco, R]]
[[Category: Brandao-Neto J]]
[[Category: Nettleship, J E]]
[[Category: DeMarco R]]
[[Category: Owens, R J]]
[[Category: Nettleship JE]]
[[Category: Pereira, H M]]
[[Category: Owens RJ]]
[[Category: Romanello, L]]
[[Category: Pereira HM]]
[[Category: Torini, J R.S]]
[[Category: Romanello L]]
[[Category: Enzyme]]
[[Category: Torini JRS]]
[[Category: Hypoxanthine-guanine phosphoribosyltransferase]]
[[Category: Transferase]]