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==Ligand-triggered allosteric ADP release primes a plant NLR complex==
==Ligand-triggered allosteric ADP release primes a plant NLR complex==
<StructureSection load='6j5w' size='340' side='right'caption='[[6j5w]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
<SX load='6j5w' size='340' side='right' viewer='molstar' caption='[[6j5w]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6j5w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J5W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J5W FirstGlance]. <br>
<table><tr><td colspan='2'>[[6j5w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J5W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J5W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j5w OCA], [http://pdbe.org/6j5w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j5w RCSB], [http://www.ebi.ac.uk/pdbsum/6j5w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j5w ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j5w OCA], [https://pdbe.org/6j5w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j5w RCSB], [https://www.ebi.ac.uk/pdbsum/6j5w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j5w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/R13L4_ARATH R13L4_ARATH]] CC-NB-LRR receptor-like protein required for recognition of the Pseudomonas syringae type III effector HopZ1a. Confers allele-specific recognition and virulence attenuation of HopZ1a. Immunity mediated by ZAR1 is independent of several genes required by other resistance protein signaling pathways such as NDR1 and RAR1.<ref>PMID:20368970</ref>
[https://www.uniprot.org/uniprot/ZRK1_ARATH ZRK1_ARATH] Serine/threonine-protein kinase that confers a broad-spectrum quantitative disease resistance (QDR) to the pathogenic biotrophic bacteria Xanthomonas campestris (e.g. pv. campestris (Xcc), pv. raphani, pv. armoriaceae and pv. incanae) by restricting bacterial spread to the vascular system from the infection site; X.campestris causes black rot disease in crops (PubMed:24068949, PubMed:26355215, PubMed:30948526). Seems to not have any kinase activity (PubMed:24068949).<ref>PMID:24068949</ref> <ref>PMID:26355215</ref> <ref>PMID:30948526</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hongwei, W]]
[[Category: Chai JJ]]
[[Category: Jianmin, Z]]
[[Category: Hu MJ]]
[[Category: Jijie, C]]
[[Category: Wang HW]]
[[Category: Jizong, W]]
[[Category: Wang J]]
[[Category: Meijuan, H]]
[[Category: Wang JZ]]
[[Category: Jia, W]]
[[Category: Zhou JM]]
[[Category: Plant protein]]
[[Category: Rks1]]
[[Category: Zar1]]

Latest revision as of 10:36, 27 March 2024

Ligand-triggered allosteric ADP release primes a plant NLR complex

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