6j06: Difference between revisions
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<StructureSection load='6j06' size='340' side='right'caption='[[6j06]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='6j06' size='340' side='right'caption='[[6j06]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6j06]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6j06]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J06 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=99C:(2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl+trihydrogen+diphosphate'>99C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=99C:(2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl+trihydrogen+diphosphate'>99C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j06 OCA], [https://pdbe.org/6j06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j06 RCSB], [https://www.ebi.ac.uk/pdbsum/6j06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j06 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cai | [[Category: Cai NN]] | ||
[[Category: Chen | [[Category: Chen CC]] | ||
[[Category: Guo | [[Category: Guo RT]] | ||
[[Category: Liu | [[Category: Liu WD]] | ||
[[Category: Yang | [[Category: Yang YY]] | ||
[[Category: Zhang | [[Category: Zhang YH]] | ||