4nnl: Difference between revisions

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<StructureSection load='4nnl' size='340' side='right'caption='[[4nnl]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4nnl' size='340' side='right'caption='[[4nnl]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sfj|3sfj]], [[4nnm|4nnm]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TAX1BP3, TIP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [https://pdbe.org/4nnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [https://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [http://pdbe.org/4nnl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [http://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TX1B3_HUMAN TX1B3_HUMAN]] May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.<ref>PMID:10940294</ref> <ref>PMID:16855024</ref> <ref>PMID:21139582</ref>
[https://www.uniprot.org/uniprot/TX1B3_HUMAN TX1B3_HUMAN] May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.<ref>PMID:10940294</ref> <ref>PMID:16855024</ref> <ref>PMID:21139582</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Amacher, J F]]
[[Category: Amacher JF]]
[[Category: Madden, D R]]
[[Category: Madden DR]]
[[Category: Pdz]]
[[Category: Pdz-peptide]]
[[Category: Protein binding]]
[[Category: Tax-interacting protein-1]]
[[Category: Tip-1]]
Retrieved from "https://proteopedia.org/4nnl"