4pde: Difference between revisions

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<StructureSection load='4pde' size='340' side='right'caption='[[4pde]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='4pde' size='340' side='right'caption='[[4pde]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PDE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fdhD, BN17_38461 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pde OCA], [http://pdbe.org/4pde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pde RCSB], [http://www.ebi.ac.uk/pdbsum/4pde PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pde ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pde OCA], [https://pdbe.org/4pde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pde RCSB], [https://www.ebi.ac.uk/pdbsum/4pde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pde ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/J7QY30_ECOLX J7QY30_ECOLX]] Necessary for formate dehydrogenase activity.[HAMAP-Rule:MF_00187][SAAS:SAAS00093836]
[https://www.uniprot.org/uniprot/FDHD_ECOLI FDHD_ECOLI] Required for formate dehydrogenase (FDH) activity (PubMed:3077634, PubMed:8522521, PubMed:22194618, PubMed:25649206). Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Specifically interacts with IscS and stimulates its cysteine desulfurase activity. Also binds the molybdenum cofactor (PubMed:22194618, PubMed:25649206). Required for activity of formate dehydrogenase N (FDH-N), formate dehydrogenase O (FDH-O) and formate dehydrogenase H (FDH-H) (PubMed:3077634, PubMed:8522521, PubMed:22194618).<ref>PMID:22194618</ref> <ref>PMID:25649206</ref> <ref>PMID:3077634</ref> <ref>PMID:8522521</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arnoux, P]]
[[Category: Arnoux P]]
[[Category: Magalon, A]]
[[Category: Magalon A]]
[[Category: Pignol, D]]
[[Category: Pignol D]]
[[Category: Walburger, A]]
[[Category: Walburger A]]
[[Category: Gdp]]
[[Category: Hydrolase]]
[[Category: Mo-bispgd sulfuration]]