4uwf: Difference between revisions

<table><tr><td colspan='2'>[[4uwf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UWF FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EUT:(8S)-9-[3,5-BIS(FLUORANYL)PHENYL]-2-MORPHOLIN-4-YL-8-(TRIFLUOROMETHYL)-7,8-DIHYDRO-6H-PYRIMIDO[1,2-A]PYRIMIDIN-4-ONE'>EUT</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uwf OCA], [https://pdbe.org/4uwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uwf RCSB], [https://www.ebi.ac.uk/pdbsum/4uwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uwf ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PK3C3_HUMAN PK3C3_HUMAN] Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.<ref>PMID:7628435</ref> <ref>PMID:14617358</ref> <ref>PMID:20208530</ref>  

*[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]]

[[Category: Homo sapiens]]

[[Category: Abecassis PY]]

[[Category: Arigon J]]

[[Category: Barriere C]]

[[Category: Benard T]]

[[Category: Bertin L]]

[[Category: Bertrand T]]

[[Category: Bretin F]]

[[Category: Brollo M]]

[[Category: Caron A]]

[[Category: Castell C]]

[[Category: Clement J]]

[[Category: Combet R]]

[[Category: Delbarre L]]

[[Category: Durand F]]

[[Category: Dureuil C]]

[[Category: El-Ahmad Y]]

[[Category: ElBatti S]]

[[Category: Fassy F]]

[[Category: Filoche-Romme B]]

[[Category: Garcia-Echeverria C]]

[[Category: Gay F]]

[[Category: Goulaouic H]]

[[Category: Labrosse JR]]

[[Category: Lefrancois D]]

[[Category: Leroy V]]

[[Category: Letallec JP]]

[[Category: Loyau V]]

[[Category: Marquette JP]]

[[Category: Mathieu M]]

[[Category: McCort G]]

[[Category: Michot N]]

[[Category: Pasquier B]]

[[Category: Perraut P]]

[[Category: Pilorge F]]

[[Category: Richepin P]]

[[Category: Ronan B]]

[[Category: Schio L]]

[[Category: Sonnefraud V]]