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==Cryo-EM structure of the yeast Ctf3 complex==
==Cryo-EM structure of the yeast Ctf3 complex==
<StructureSection load='6oua' size='340' side='right'caption='[[6oua]], [[Resolution|resolution]] 4.18&Aring;' scene=''>
<SX load='6oua' size='340' side='right' viewer='molstar' caption='[[6oua]], [[Resolution|resolution]] 4.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6oua]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OUA FirstGlance]. <br>
<table><tr><td colspan='2'>[[6oua]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OUA FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nuw|6nuw]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.18&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6oua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oua OCA], [http://pdbe.org/6oua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6oua RCSB], [http://www.ebi.ac.uk/pdbsum/6oua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6oua ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6oua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oua OCA], [https://pdbe.org/6oua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6oua RCSB], [https://www.ebi.ac.uk/pdbsum/6oua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6oua ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CENPI_YEAST CENPI_YEAST]] Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation.  Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.<ref>PMID:12408861</ref> [[http://www.uniprot.org/uniprot/CENPK_YEAST CENPK_YEAST]] Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.<ref>PMID:9987135</ref>  [[http://www.uniprot.org/uniprot/CENPH_YEAST CENPH_YEAST]] Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.<ref>PMID:9862478</ref> 
[https://www.uniprot.org/uniprot/CENPI_YEAST CENPI_YEAST] Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation.  Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.<ref>PMID:12408861</ref>  
 
==See Also==
*[[Centromere protein 3D structure|Centromere protein 3D structure]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Harrison, S C]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Hinshaw, S M]]
[[Category: Harrison SC]]
[[Category: Cell cycle]]
[[Category: Hinshaw SM]]
[[Category: Chromosome]]
[[Category: Cryo-em]]
[[Category: Kinetochore]]
Retrieved from "https://proteopedia.org/6oua"