5a7h: Difference between revisions

<table><tr><td colspan='2'>[[5a7h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A7H FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a7h OCA], [https://pdbe.org/5a7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a7h RCSB], [https://www.ebi.ac.uk/pdbsum/5a7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a7h ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/EST1_HUMAN EST1_HUMAN] Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.<ref>PMID:7980644</ref> <ref>PMID:9169443</ref>  

[[Category: Homo sapiens]]

[[Category: Arena de Souza V]]

[[Category: Charlton M]]

[[Category: Owen RJ]]

[[Category: Scott DJ]]

[[Category: Walsh MA]]