6hyn: Difference between revisions
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<StructureSection load='6hyn' size='340' side='right'caption='[[6hyn]], [[Resolution|resolution]] 1.14Å' scene=''> | <StructureSection load='6hyn' size='340' side='right'caption='[[6hyn]], [[Resolution|resolution]] 1.14Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6hyn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6hyn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HYN FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hyn OCA], [https://pdbe.org/6hyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hyn RCSB], [https://www.ebi.ac.uk/pdbsum/6hyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hyn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ATG13_HUMAN ATG13_HUMAN] Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.<ref>PMID:19287211</ref> <ref>PMID:19211835</ref> <ref>PMID:19225151</ref> <ref>PMID:21855797</ref> <ref>PMID:18936157</ref> <ref>PMID:21795849</ref> [https://www.uniprot.org/uniprot/GBRAP_HUMAN GBRAP_HUMAN] May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity).<ref>PMID:15977068</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6hyn" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6hyn" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[GABA receptor-associated protein 3D structures|GABA receptor-associated protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Johansen | [[Category: Johansen T]] | ||
[[Category: Joshi | [[Category: Joshi D]] | ||
[[Category: Mouilleron | [[Category: Mouilleron S]] | ||
[[Category: Nyoni | [[Category: Nyoni L]] | ||
[[Category: | [[Category: O'Reilly N]] | ||
[[Category: | [[Category: Razi M]] | ||
[[Category: Tooze | [[Category: Tooze S]] | ||
[[Category: Wirth | [[Category: Wirth M]] | ||
[[Category: Zhang | [[Category: Zhang W]] | ||
