6qe0: Difference between revisions

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<StructureSection load='6qe0' size='340' side='right'caption='[[6qe0]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
<StructureSection load='6qe0' size='340' side='right'caption='[[6qe0]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6qe0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QE0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QE0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6qe0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QE0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HZ2:(2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic+acid'>HZ2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.394&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qdx|6qdx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HZ2:(2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic+acid'>HZ2</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yhiR, rlmJ, PPECC33_03818 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qe0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qe0 OCA], [https://pdbe.org/6qe0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qe0 RCSB], [https://www.ebi.ac.uk/pdbsum/6qe0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qe0 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/23S_rRNA_(adenine(2030)-N(6))-methyltransferase 23S rRNA (adenine(2030)-N(6))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.266 2.1.1.266] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qe0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qe0 OCA], [http://pdbe.org/6qe0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qe0 RCSB], [http://www.ebi.ac.uk/pdbsum/6qe0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qe0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A0G3KF30_ECOLX A0A0G3KF30_ECOLX]] Specifically methylates the adenine in position 2030 of 23S rRNA.[HAMAP-Rule:MF_00934]
[https://www.uniprot.org/uniprot/RLMJ_ECOLI RLMJ_ECOLI] Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.<ref>PMID:16707682</ref> <ref>PMID:22847818</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Atdjian, C]]
[[Category: Atdjian C]]
[[Category: Barraud, P]]
[[Category: Barraud P]]
[[Category: Brachet, F]]
[[Category: Brachet F]]
[[Category: Braud, E]]
[[Category: Braud E]]
[[Category: Catala, M]]
[[Category: Catala M]]
[[Category: Droogmans, L]]
[[Category: Droogmans L]]
[[Category: Etheve-Quelquejeu, M]]
[[Category: Etheve-Quelquejeu M]]
[[Category: Iannazzo, L]]
[[Category: Iannazzo L]]
[[Category: Oerum, S]]
[[Category: Oerum S]]
[[Category: Ponchon, L]]
[[Category: Ponchon L]]
[[Category: Tisne, C]]
[[Category: Tisne C]]
[[Category: Inhibitor]]
[[Category: M1a]]
[[Category: M6a]]
[[Category: Methyltransferase]]
[[Category: Rlmj]]
[[Category: Rna binding]]
[[Category: Rna mtase]]
[[Category: Structure]]
[[Category: Transferase]]
[[Category: Transition state analogue]]
[[Category: Trmk]]
Retrieved from "https://proteopedia.org/6qe0"