2c56: Difference between revisions
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<StructureSection load='2c56' size='340' side='right'caption='[[2c56]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2c56' size='340' side='right'caption='[[2c56]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c56]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2c56]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C56 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C56 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c56 OCA], [https://pdbe.org/2c56 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c56 RCSB], [https://www.ebi.ac.uk/pdbsum/2c56 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c56 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/UNG_HHV11 UNG_HHV11] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosine. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly, in terminally differentiated neurons which lack DNA repair enzymes.<ref>PMID:7552746</ref> <ref>PMID:16306042</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human alphaherpesvirus 1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baldwin GS]] | |||
[[Category: Baldwin | [[Category: Bellamy SRW]] | ||
[[Category: Bellamy | [[Category: Carpenter EP]] | ||
[[Category: Carpenter | [[Category: Krusong K]] | ||
[[Category: Krusong | [[Category: Savva R]] | ||
[[Category: Savva | |||