4v36: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(One intermediate revision by the same user not shown)
Line 3: Line 3:
<StructureSection load='4v36' size='340' side='right'caption='[[4v36]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4v36' size='340' side='right'caption='[[4v36]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4v36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"clostridium_licheniforme"_weigmann_1898 "clostridium licheniforme" weigmann 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V36 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4v36]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V36 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LYN:2,6-DIAMINO-HEXANOIC+ACID+AMIDE'>LYN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4v34|4v34]], [[4v35|4v35]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LYN:2,6-DIAMINO-HEXANOIC+ACID+AMIDE'>LYN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysyltransferase Lysyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.3 2.3.2.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v36 OCA], [https://pdbe.org/4v36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v36 RCSB], [https://www.ebi.ac.uk/pdbsum/4v36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v36 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v36 OCA], [http://pdbe.org/4v36 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v36 RCSB], [http://www.ebi.ac.uk/pdbsum/4v36 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4v36 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q65MA9_BACLD Q65MA9_BACLD] Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.[RuleBase:RU363042]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clostridium licheniforme weigmann 1898]]
[[Category: Bacillus licheniformis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lysyltransferase]]
[[Category: Hebecker S]]
[[Category: Hebecker, S]]
[[Category: Heinz DW]]
[[Category: Heinz, D W]]
[[Category: Krausze J]]
[[Category: Krausze, J]]
[[Category: Moser J]]
[[Category: Moser, J]]
[[Category: Bacterial resistance protein]]
[[Category: L-pg]]
[[Category: Lipid homeostasis]]
[[Category: Lysine amide]]
[[Category: Phenix. mr_rosetta]]
[[Category: T-rna dependent aminoacylation]]
[[Category: Transferase]]
[[Category: Yfix]]
Retrieved from "https://proteopedia.org/4v36"