6rsb: Difference between revisions

(One intermediate revision by the same user not shown)

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6rsb is ~~ON HOLD~~

==Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSB OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6RSB FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KGZ:1-[(3~{R},4~{R})-4-(cyanomethyl)-1-[[4-(cyclohexen-1-yl)phenyl]methyl]-3-fluoranyl-piperidin-4-yl]-3-(cyclopropylcarbonylamino)pyrazole-4-carboxamide'>KGZ</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6rsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rsb OCA], [https://pdbe.org/6rsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rsb RCSB], [https://www.ebi.ac.uk/pdbsum/6rsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rsb ProSAT]</td></tr>

</table>

~~Authors~~:

==See Also==

*[[Janus kinase 3D structures|Janus kinase 3D structures]]

~~Description~~:

__TOC__

[[Category: ~~Unreleased Structures~~]]

</StructureSection>

[[Category: Large Structures]]

[[Category: Brown DG]]

[[Category: Lupardus PJ]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6rsb is ON HOLD
+==Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class==
+<StructureSection load='6rsb' size='340' side='right'caption='[[6rsb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RSB FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KGZ:1-[(3~{R},4~{R})-4-(cyanomethyl)-1-[[4-(cyclohexen-1-yl)phenyl]methyl]-3-fluoranyl-piperidin-4-yl]-3-(cyclopropylcarbonylamino)pyrazole-4-carboxamide'>KGZ</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rsb OCA], [https://pdbe.org/6rsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rsb RCSB], [https://www.ebi.ac.uk/pdbsum/6rsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rsb ProSAT]</span></td></tr>
+</table>
-Authors:
+==See Also==
+*[[Janus kinase 3D structures|Janus kinase 3D structures]]
-Description:
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Brown DG]]
+[[Category: Lupardus PJ]]