Dioxygenase: Difference between revisions
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<StructureSection size="" scene ="Journal:JBIC:5/Opening/2" caption="Solved Crystal Structure of Hyperactive Catechol Dioxygenase"> | <StructureSection size="" scene ="Journal:JBIC:5/Opening/2" caption="Solved Crystal Structure of Hyperactive Catechol Dioxygenase"> | ||
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== Function == | == Function == | ||
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* '''Glyoxalase/bleomycin resistant protein/dioxygenase''' (GBD) catalyzes the cleavage of S-lactoyl-glutathione to methylglyoxal and glutathione.<br /> | * '''Glyoxalase/bleomycin resistant protein/dioxygenase''' (GBD) catalyzes the cleavage of S-lactoyl-glutathione to methylglyoxal and glutathione.<br /> | ||
* '''Methylcytosine dioxygenase''' (TET) catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine to mediate DNA demethylation<ref>PMID:25862091</ref>. For details see [[TET Enzymes]].<br /> | * '''Methylcytosine dioxygenase''' (TET) catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine to mediate DNA demethylation<ref>PMID:25862091</ref>. For details see [[TET Enzymes]].<br /> | ||
* '''α-ketoglutarate-dependent dioxygenase Alkb''' repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation<ref>PMID:18432238</ref>.<br /> | |||
* '''α-ketoglutarate-dependent dioxygenase Fto''' highest activity is repairing alkylated RNA containing 3-methyluracil by oxidative demethylation<ref>PMID:18775698</ref>.<br /> | |||
== A Hyperactive Cobalt-Substituted Extradiol-Cleaving Catechol Dioxygenase <ref>DOI 10.1007/s00775-010-0732-0</ref>== | == A Hyperactive Cobalt-Substituted Extradiol-Cleaving Catechol Dioxygenase <ref>DOI 10.1007/s00775-010-0732-0</ref>== | ||
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</StructureSection> | </StructureSection> | ||
==References== | |||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
