6pb5: Difference between revisions
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New page: '''Unreleased structure''' The entry 6pb5 is ON HOLD Authors: Description: Category: Unreleased Structures |
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The | ==The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture== | ||
<StructureSection load='6pb5' size='340' side='right'caption='[[6pb5]], [[Resolution|resolution]] 4.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6pb5]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PB5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.52Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pb5 OCA], [https://pdbe.org/6pb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pb5 RCSB], [https://www.ebi.ac.uk/pdbsum/6pb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pb5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref> | |||
==See Also== | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
*[[Sigma factor 3D structures|Sigma factor 3D structures]] | |||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu B]] | |||
[[Category: Shi W]] | |||