6pdm: Difference between revisions

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'''Unreleased structure'''


The entry 6pdm is ON HOLD
==Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)==
 
<StructureSection load='6pdm' size='340' side='right'caption='[[6pdm]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
Authors: Halabelian, L., Tempel, W., Zeng, H., Li, Y., Seitova, A., Hutchinson, A., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6pdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PDM FirstGlance]. <br>
Description: Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
[[Category: Hutchinson, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pdm OCA], [https://pdbe.org/6pdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pdm RCSB], [https://www.ebi.ac.uk/pdbsum/6pdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pdm ProSAT]</span></td></tr>
[[Category: Edwards, A.M]]
</table>
[[Category: Arrowsmith, C.H]]
== Function ==
[[Category: Seitova, A]]
[https://www.uniprot.org/uniprot/ANM9_HUMAN ANM9_HUMAN] Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA (PubMed:25737013, PubMed:25979344).<ref>PMID:25737013</ref> <ref>PMID:25979344</ref>
[[Category: Structural Genomics Consortium (Sgc)]]
== References ==
[[Category: Li, Y]]
<references/>
[[Category: Halabelian, L]]
__TOC__
[[Category: Zeng, H]]
</StructureSection>
[[Category: Bountra, C]]
[[Category: Homo sapiens]]
[[Category: Tempel, W]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: Halabelian L]]
[[Category: Hutchinson A]]
[[Category: Li Y]]
[[Category: Seitova A]]
[[Category: Tempel W]]
[[Category: Zeng H]]
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