1imt: Difference between revisions
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==MAMBA INTESTINAL TOXIN 1, NMR, 39 STRUCTURES== | ==MAMBA INTESTINAL TOXIN 1, NMR, 39 STRUCTURES== | ||
<StructureSection load='1imt' size='340' side='right'caption='[[1imt | <StructureSection load='1imt' size='340' side='right'caption='[[1imt]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1imt]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1imt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IMT FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 39 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1imt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1imt OCA], [https://pdbe.org/1imt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1imt RCSB], [https://www.ebi.ac.uk/pdbsum/1imt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1imt ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MIT1_DENPO MIT1_DENPO] Potently contracts gastrointestinal (GI) smooth muscle. The receptor for this toxin is present both in the CNS and in the smooth muscle and may be a potassium channel.<ref>PMID:10567694</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/1imt_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/1imt_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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[[Category: Dendroaspis polylepis polylepis]] | [[Category: Dendroaspis polylepis polylepis]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Albrand | [[Category: Albrand J-P]] | ||
[[Category: Blackledge | [[Category: Blackledge M]] | ||
[[Category: Boisbouvier | [[Category: Boisbouvier J]] | ||
[[Category: Jaquinod | [[Category: Jaquinod M]] | ||
[[Category: Lazdunski | [[Category: Lazdunski M]] | ||
[[Category: Marion | [[Category: Marion D]] | ||
[[Category: Schweitz | [[Category: Schweitz H]] | ||
