6pk2: Difference between revisions

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'''Unreleased structure'''


The entry 6pk2 is ON HOLD
==CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS==
 
<StructureSection load='6pk2' size='340' side='right'caption='[[6pk2]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6pk2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PK2 FirstGlance]. <br>
Description: CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.402&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ORJ:2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide'>ORJ</scene></td></tr>
[[Category: Michele, T.C.B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pk2 OCA], [https://pdbe.org/6pk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pk2 RCSB], [https://www.ebi.ac.uk/pdbsum/6pk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pk2 ProSAT]</span></td></tr>
[[Category: Reddy, M.C.M]]
</table>
[[Category: Nian, Z]]
== Function ==
[[Category: Sacchettini, J.C]]
[https://www.uniprot.org/uniprot/ACCD6_MYCTU ACCD6_MYCTU] Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).<ref>PMID:17114269</ref>
[[Category: Tb Structural Genomics Consortium (Tbsgc)]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Michele TCB]]
[[Category: Nian Z]]
[[Category: Reddy MCM]]
[[Category: Sacchettini JC]]