6pk7: Difference between revisions
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==cryoEM structure of the product-bound human CTP synthase 2 filament== | |||
<SX load='6pk7' size='340' side='right' viewer='molstar' caption='[[6pk7]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6pk7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PK7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pk7 OCA], [https://pdbe.org/6pk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pk7 RCSB], [https://www.ebi.ac.uk/pdbsum/6pk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pk7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PYRG2_HUMAN PYRG2_HUMAN] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.<ref>PMID:10899599</ref> <ref>PMID:16179339</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Kollman JM]] | |||
[[Category: Lynch EM]] | |||
Latest revision as of 09:26, 20 March 2024
cryoEM structure of the product-bound human CTP synthase 2 filament
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