6p9e: Difference between revisions

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<StructureSection load='6p9e' size='340' side='right'caption='[[6p9e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6p9e' size='340' side='right'caption='[[6p9e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6p9e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P9E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P9E FirstGlance]. <br>
<table><tr><td colspan='2'>[[6p9e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P9E FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=O6D:(2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic+acid'>O6D</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL36G, IL1E, IL1F9, IL1H1, IL1RP2, UNQ2456/PRO5737 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O6D:(2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic+acid'>O6D</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p9e OCA], [http://pdbe.org/6p9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p9e RCSB], [http://www.ebi.ac.uk/pdbsum/6p9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p9e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p9e OCA], [https://pdbe.org/6p9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p9e RCSB], [https://www.ebi.ac.uk/pdbsum/6p9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p9e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IL36G_HUMAN IL36G_HUMAN]] Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.  
[https://www.uniprot.org/uniprot/IL36G_HUMAN IL36G_HUMAN] Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6p9e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6p9e" style="background-color:#fffaf0;"></div>
==See Also==
*[[Interleukin 3D structures|Interleukin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Argiriadi, M A]]
[[Category: Argiriadi MA]]
[[Category: Gerstein, C E]]
[[Category: Gerstein CE]]
[[Category: Gopalakrishnan, S M]]
[[Category: Gopalakrishnan SM]]
[[Category: Henry, R F]]
[[Category: Henry RF]]
[[Category: Herold, J M]]
[[Category: Herold JM]]
[[Category: Honore, P]]
[[Category: Honore P]]
[[Category: Kakavas, S J]]
[[Category: Kakavas SJ]]
[[Category: McDonald, H A]]
[[Category: McDonald HA]]
[[Category: McGaraughty, S P]]
[[Category: McGaraughty SP]]
[[Category: Medina, L]]
[[Category: Medina L]]
[[Category: Paulsboe, S E]]
[[Category: Paulsboe SE]]
[[Category: Putman, B]]
[[Category: Putman B]]
[[Category: Qiu, W]]
[[Category: Qiu W]]
[[Category: Richardson, P L]]
[[Category: Richardson PL]]
[[Category: Sadhukhan, R]]
[[Category: Sadhukhan R]]
[[Category: Salte, K M]]
[[Category: Salte KM]]
[[Category: Scott, V E]]
[[Category: Scott VE]]
[[Category: Shotwell, J B]]
[[Category: Shotwell JB]]
[[Category: Sielaff, B]]
[[Category: Sielaff B]]
[[Category: Stockmann, H]]
[[Category: Stockmann H]]
[[Category: Su, Z]]
[[Category: Su Z]]
[[Category: Sun, C C]]
[[Category: Sun CC]]
[[Category: Sun, Q]]
[[Category: Sun Q]]
[[Category: Todorovic, T]]
[[Category: Todorovic T]]
[[Category: Wetter, J B]]
[[Category: Wetter JB]]
[[Category: Cytokine]]
[[Category: Il-36]]
[[Category: Small molecule antagonist]]
Retrieved from "https://proteopedia.org/6p9e"