4yzy: Difference between revisions

<table><tr><td colspan='2'>[[4yzy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YZY FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yzy OCA], [https://pdbe.org/4yzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yzy RCSB], [https://www.ebi.ac.uk/pdbsum/4yzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yzy ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/E2AK3_MOUSE E2AK3_MOUSE] Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1).<ref>PMID:11035797</ref>  

[[Category: Mus musculus]]

[[Category: Ali MMU]]

[[Category: Carrara M]]

[[Category: Prischi F]]