|
|
| (One intermediate revision by one other user not shown) |
| Line 1: |
Line 1: |
| <StructureSection load='1aik' size='340' side='right' caption='Core structure of acetylated gp41 from the HIV envelope glycoprotein, [[1aik]].' scene=''> | | <StructureSection load='1aik' size='340' side='right' caption='Core structure of acetylated gp41 from the HIV envelope glycoprotein, [[1aik]].' scene=''> |
| == Function == | | == Function == |
| '''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins]]. | | '''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins|HIV-1 viral envelope proteins]]. |
|
| |
|
| == Relevance == | | == Relevance == |
| Line 10: |
Line 10: |
|
| |
|
| </StructureSection> | | </StructureSection> |
| == 3D Structures of Gp41 ==
| |
|
| |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| |
| {{#tree:id=OrganizedByTopic|openlevels=0|
| |
|
| |
| *Gp41 from HIV-1; Domains – core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854
| |
|
| |
| **[[2zfc]], [[3u91]] – Gp41 N-terminal residues 1-49 <br />
| |
| **[[3k9a]] – Gp41 residues 1-108 (mutant)<br />
| |
| **[[1aik]], [[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]], [[1szt]], [[3vu5]], [[3vu6]] - Gp41 N-peptide domain <br />
| |
| **[[1env]], [[3cp1]], [[3cyo]], [[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]], [[5ka6]], [[5ka5]], [[4i2l]] – Gp41 N-peptide domain (mutant)<br />
| |
| **[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[5h0n]], [[5zpw]] – Gp41 N-peptide domain + fusion inhibitor peptide<br />
| |
| **[[6b3u]], [[6dln]] – Gp41 transmembrane domain - NMR<br />
| |
| **[[5vwl]] – Gp41 tail domain - NMR<br />
| |
| **[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6ck9]], [[6chb]], [[6ch9]], [[6ch8]], [[6ch7]], [[5w6d]], [[4nrx]], [[5fyk]], [[5fyj]], [[4nco]], [[6mdt]], [[6mco]] – Gp41 core + Gp120 + antibody<br />
| |
| **[[6nnj]], [[6nnf]], [[6nm6]] – Gp41 core (mutant) + Gp120 + antibody<br />
| |
| **[[6cdi]], [[6orn]], [[6oo]], [[6orp]], [[6orq]], [[6okp]], [[6nqd]], [[6mn7]], [[6cuf]], [[6cue]] – Gp41 core + Gp120 + antibody – Cryo EM<br />
| |
| **[[6nc3]], [[6nc2]] – Gp41 core (mutant) + Gp120 + antibody – Cryo EM<br />
| |
| **[[5u1f]], [[5thr]] – Gp41 core + Gp120 + antibody + CD4<br />
| |
| **[[5hm1]] – Gp41 core + llama antibody <br />
| |
| **[[3o3x]] – arGp41 - artificial<br />
| |
| **[[4dzu]] – arGp41 + 3-α<br />
| |
| **[[4dzv]] – arGp41 + 4-α/β<br />
| |
|
| |
| *Gp41 from Simian Immunodeficiency Virus
| |
|
| |
|
| **[[2siv]] – Gp41 core<br />
| |
| **[[2ezo]], [[2ezp]], [[2ezq]], [[2ezr]], [[2ezs]], [[1qce]] – Gp41 core - NMR<br />
| |
| **[[1qbz]], [[1jq0]] – Gp41 core (mutant)<br />
| |
| }}
| |
| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |
