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[[Image:2jg0.gif|left|200px]]<br />
<applet load="2jg0" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2jg0, resolution 1.50&Aring;" />
'''FAMILY 37 TREHALASE FROM ESCHERICHIA COLI IN COMPLEX WITH 1-THIATREHAZOLIN'''<br />


==About this Structure==
==Family 37 trehalase from Escherichia coli in complex with 1- thiatrehazolin==
2JG0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with TTZ as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Alpha,alpha-trehalase Alpha,alpha-trehalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.28 3.2.1.28] Structure known Active Site: ACD. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JG0 OCA].
<StructureSection load='2jg0' size='340' side='right'caption='[[2jg0]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
[[Category: Alpha,alpha-trehalase]]
== Structural highlights ==
[[Category: Escherichia coli]]
<table><tr><td colspan='2'>[[2jg0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JG0 FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
[[Category: Chiara, J.L.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TTZ:N-[(3AS,4R,5S,6S,6AS)-4,5,6-TRIHYDROXY-4-(HYDROXYMETHYL)-4,5,6,6A-TETRAHYDRO-3AH-CYCLOPENTA[D][1,3]THIAZOL-2-YL]-ALPHA-D-GLUCOPYRANOSYLAMINE'>TTZ</scene></td></tr>
[[Category: Davies, G.J.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jg0 OCA], [https://pdbe.org/2jg0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jg0 RCSB], [https://www.ebi.ac.uk/pdbsum/2jg0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jg0 ProSAT]</span></td></tr>
[[Category: Garcia, A.]]
</table>
[[Category: Gibson, R.P.]]
== Function ==
[[Category: Gloster, T.M.]]
[https://www.uniprot.org/uniprot/TREA_ECOLI TREA_ECOLI] Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.[HAMAP-Rule:MF_01060]
[[Category: Gracia, I.Storch.De.]]
== Evolutionary Conservation ==
[[Category: Roberts, S.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Warren, R.A.J.]]
Check<jmol>
[[Category: TTZ]]
  <jmolCheckbox>
[[Category: 1-thiatrehazolin]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/2jg0_consurf.spt"</scriptWhenChecked>
[[Category: family 37]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: glycosidase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: glycoside hydrolase]]
  </jmolCheckbox>
[[Category: hydrolase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jg0 ConSurf].
[[Category: inhibitor]]
<div style="clear:both"></div>
[[Category: periplasmic]]
__TOC__
[[Category: trehalase]]
</StructureSection>
 
[[Category: Escherichia coli K-12]]
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov  5 18:34:11 2007''
[[Category: Large Structures]]
[[Category: Chiara JL]]
[[Category: Davies GJ]]
[[Category: Garcia A]]
[[Category: Gibson RP]]
[[Category: Gloster TM]]
[[Category: Roberts S]]
[[Category: Storch De Gracia I]]
[[Category: Warren RAJ]]

Latest revision as of 07:56, 23 October 2024

Family 37 trehalase from Escherichia coli in complex with 1- thiatrehazolin

2jg0, resolution 1.50Å

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