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==Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state B2==
==Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state B2==
<StructureSection load='6rxv' size='340' side='right'caption='[[6rxv]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
<SX load='6rxv' size='340' side='right' viewer='molstar' caption='[[6rxv]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6rxv]] is a 68 chain structure with sequence from [http://en.wikipedia.org/wiki/Chaetomium_thermophilum_(strain_dsm_1495_/_cbs_144.50_/_imi_039719) Chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RXV FirstGlance]. <br>
<table><tr><td colspan='2'>[[6rxv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RXV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rxv OCA], [http://pdbe.org/6rxv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rxv RCSB], [http://www.ebi.ac.uk/pdbsum/6rxv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rxv ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rxv OCA], [https://pdbe.org/6rxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rxv RCSB], [https://www.ebi.ac.uk/pdbsum/6rxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rxv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/G0S3V7_CHATD G0S3V7_CHATD]] Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.[PIRNR:PIRNR006515] [[http://www.uniprot.org/uniprot/PNO1_CHATD PNO1_CHATD]] Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.[UniProtKB:Q99216] [[http://www.uniprot.org/uniprot/UTP11_CHATD UTP11_CHATD]] Involved in nucleolar processing of pre-18S ribosomal RNA.[UniProtKB:P34247] [[http://www.uniprot.org/uniprot/NOL10_CHATD NOL10_CHATD]] May be involved in rRNA-processing and ribosome biosynthesis.[UniProtKB:P48234]  
[https://www.uniprot.org/uniprot/G0SF93_CHATD G0SF93_CHATD]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6rxv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6rxv" style="background-color:#fffaf0;"></div>
==See Also==
*[[Ribosome 3D structures|Ribosome 3D structures]]
*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Beckmann, R]]
[[Category: Beckmann R]]
[[Category: Berninghausen, O]]
[[Category: Berninghausen O]]
[[Category: Cheng, J]]
[[Category: Cheng J]]
[[Category: Griesel, S]]
[[Category: Griesel S]]
[[Category: Hurt, E]]
[[Category: Hurt E]]
[[Category: Kellner, N]]
[[Category: Kellner N]]
[[Category: Ribosome]]
[[Category: Ribosome biogenesis]]
[[Category: Rrna]]
Retrieved from "https://proteopedia.org/6rxv"