6kq9: Difference between revisions
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==A long chain secondary alcohol dehydrogenase of Micrococcus luteus== | |||
<StructureSection load='6kq9' size='340' side='right'caption='[[6kq9]], [[Resolution|resolution]] 2.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6kq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Micrococcus_luteus Micrococcus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KQ9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.251Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kq9 OCA], [https://pdbe.org/6kq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kq9 RCSB], [https://www.ebi.ac.uk/pdbsum/6kq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kq9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A4U1L6L9_MICLU A0A4U1L6L9_MICLU] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Structure-based engineering of a NAD+-dependent secondary alcohol dehydrogenase from Micrococcus luteus led to a 1800-fold increase in catalytic efficiency for NADP+. Furthermore, the engineered enzymes (e.g., D37S/A38R/V39S/T15I) were successfully coupled to a NADPH-dependent Baeyer-Villiger monooxygenase from Pseudomonas putida KT2440 for redox-neutral biotransformations of C18 fatty acids into C9 chemicals. | |||
Cofactor specificity engineering of a long-chain secondary alcohol dehydrogenase from Micrococcus luteus for redox-neutral biotransformation of fatty acids.,Seo EJ, Kim HJ, Kim MJ, Kim JS, Park JB Chem Commun (Camb). 2019 Nov 28;55(96):14462-14465. doi: 10.1039/c9cc06447h. PMID:31728457<ref>PMID:31728457</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: Kim | <div class="pdbe-citations 6kq9" style="background-color:#fffaf0;"></div> | ||
[[Category: Kim | |||
==See Also== | |||
*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Micrococcus luteus]] | |||
[[Category: Kim HJ]] | |||
[[Category: Kim JS]] | |||
Latest revision as of 10:39, 22 November 2023
A long chain secondary alcohol dehydrogenase of Micrococcus luteus
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