2x66: Difference between revisions

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<StructureSection load='2x66' size='340' side='right'caption='[[2x66]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
<StructureSection load='2x66' size='340' side='right'caption='[[2x66]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2x66]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_liquefaciens"_flugge_1886 "bacillus fluorescens liquefaciens" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X66 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X66 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2x66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X66 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2v7i|2v7i]], [[2v7k|2v7k]], [[2v7m|2v7m]], [[2v7l|2v7l]], [[2v7j|2v7j]], [[2x67|2x67]], [[2x68|2x68]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x66 OCA], [http://pdbe.org/2x66 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x66 RCSB], [http://www.ebi.ac.uk/pdbsum/2x66 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x66 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x66 OCA], [https://pdbe.org/2x66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x66 RCSB], [https://www.ebi.ac.uk/pdbsum/2x66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x66 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRNB_PSEFL PRNB_PSEFL]] Involved in the biosynthesis of the antifungal antibiotic pyrrolnitrin. Catalyzes the ring rearrangement and decarboxylation to convert 7-chloro-L-tryptophan (7-CLT) to monodechloroaminopyrrolnitrin (MDA). It can also use 7-chloro-D-tryptophan, but 7-chloro-L-tryptophan is the preferred natural enantiomer.<ref>PMID:17924666</ref> <ref>PMID:9172332</ref> <ref>PMID:9537395</ref>
[https://www.uniprot.org/uniprot/PRNB_PSEFL PRNB_PSEFL] Involved in the biosynthesis of the antifungal antibiotic pyrrolnitrin. Catalyzes the ring rearrangement and decarboxylation to convert 7-chloro-L-tryptophan (7-CLT) to monodechloroaminopyrrolnitrin (MDA). It can also use 7-chloro-D-tryptophan, but 7-chloro-L-tryptophan is the preferred natural enantiomer.<ref>PMID:17924666</ref> <ref>PMID:9172332</ref> <ref>PMID:9537395</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/2x66_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/2x66_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus fluorescens liquefaciens flugge 1886]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Naismith, J H]]
[[Category: Pseudomonas fluorescens]]
[[Category: Zhu, X]]
[[Category: Naismith JH]]
[[Category: Pee, K H.van]]
[[Category: Zhu X]]
[[Category: Biosynthetic protein]]
[[Category: Van pee K-H]]
[[Category: Indolamine/tryptophan dioxygenase superfamily]]