4ckk: Difference between revisions

<table><tr><td colspan='2'>[[4ckk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CKK FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ckk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckk OCA], [https://pdbe.org/4ckk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ckk RCSB], [https://www.ebi.ac.uk/pdbsum/4ckk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckk ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/A0A0H3JH39_ECO57 A0A0H3JH39_ECO57] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01897]

[[Category: Escherichia coli]]

[[Category: Edwards MJ]]

[[Category: Hearnshaw SJ]]

[[Category: Lawson DM]]

[[Category: Maxwell A]]

[[Category: Stevenson CEM]]