6kw5: Difference between revisions
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New page: '''Unreleased structure''' The entry 6kw5 is ON HOLD Authors: Description: Category: Unreleased Structures |
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The | ==The ClassC RSC-Nucleosome Complex== | ||
<StructureSection load='6kw5' size='340' side='right'caption='[[6kw5]], [[Resolution|resolution]] 10.13Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6kw5]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KW5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.13Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kw5 OCA], [https://pdbe.org/6kw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kw5 RCSB], [https://www.ebi.ac.uk/pdbsum/6kw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kw5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/H2A1_XENLA H2A1_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
==See Also== | |||
*[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
[[Category: | *[[Histone 3D structures|Histone 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Xenopus laevis]] | |||
[[Category: Cairns B]] | |||
[[Category: Chen KJ]] | |||
[[Category: Chen ZC]] | |||
[[Category: Gao N]] | |||
[[Category: Verma N]] | |||
[[Category: Wu H]] | |||
[[Category: Ye YP]] | |||
Latest revision as of 10:44, 27 March 2024
The ClassC RSC-Nucleosome Complex
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