6l0u: Difference between revisions
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New page: '''Unreleased structure''' The entry 6l0u is ON HOLD Authors: Jiang, L.L., Zhou, L. Description: Crystal structure of mouse glyoxalase I complexed with a small molecule inhibitor [[Cat... |
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==Crystal structure of mouse glyoxalase I complexed with a small molecule inhibitor== | |||
<StructureSection load='6l0u' size='340' side='right'caption='[[6l0u]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6l0u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L0U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E1L:N-[4-(trifluoromethyloxy)phenyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carbothioamide'>E1L</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l0u OCA], [https://pdbe.org/6l0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l0u RCSB], [https://www.ebi.ac.uk/pdbsum/6l0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l0u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity). | |||
==See Also== | |||
*[[Glyoxalase 3D structures|Glyoxalase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Jiang | [[Category: Mus musculus]] | ||
[[Category: Jiang LL]] | |||
[[Category: Zhou L]] | |||
Latest revision as of 10:48, 22 November 2023
Crystal structure of mouse glyoxalase I complexed with a small molecule inhibitor
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