6pwx: Difference between revisions

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'''Unreleased structure'''


The entry 6pwx is ON HOLD  until Paper Publication
==Cryo-EM structure of RbBP5 bound to the nucleosome==
<SX load='6pwx' size='340' side='right' viewer='molstar' caption='[[6pwx]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6pwx]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PWX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pwx OCA], [https://pdbe.org/6pwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pwx RCSB], [https://www.ebi.ac.uk/pdbsum/6pwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pwx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RBBP5_HUMAN RBBP5_HUMAN] In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.<ref>PMID:19556245</ref>


Authors:  
==See Also==
 
*[[Histone 3D structures|Histone 3D structures]]
Description:  
*[[Retinoblastoma-binding protein 3D structures|Retinoblastoma-binding protein 3D structures]]
[[Category: Unreleased Structures]]
== References ==
<references/>
__TOC__
</SX>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Xenopus laevis]]
[[Category: Ayoub A]]
[[Category: Cho U]]
[[Category: Cianfrocco MA]]
[[Category: Dou Y]]
[[Category: Lee YT]]
[[Category: Park SH]]
[[Category: Su M]]
[[Category: Xu J]]
[[Category: Zhang B]]
[[Category: Zhang W]]
[[Category: Zhang Y]]
Retrieved from "https://proteopedia.org/6pwx"