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==Crystal structure of a dehydrogenase mutant1==
==Crystal structure of RasADH F12 from Ralstonia.sp in complex with NADPH and A6O==
<StructureSection load='6ihh' size='340' side='right'caption='[[6ihh]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='6ihh' size='340' side='right'caption='[[6ihh]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ihh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IHH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IHH FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ihh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ralstonia_sp. Ralstonia sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IHH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A6O:(2R,3S)-2-ethyl-2-[(2E)-2-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-3-oxidanyl-cyclopentan-1-one'>A6O</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ihh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ihh OCA], [http://pdbe.org/6ihh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ihh RCSB], [http://www.ebi.ac.uk/pdbsum/6ihh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ihh ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A6O:(2R,3S)-2-ethyl-2-[(2E)-2-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-3-oxidanyl-cyclopentan-1-one'>A6O</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ihh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ihh OCA], [https://pdbe.org/6ihh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ihh RCSB], [https://www.ebi.ac.uk/pdbsum/6ihh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ihh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C0IR58_9RALS C0IR58_9RALS]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chen, X]]
[[Category: Ralstonia sp]]
[[Category: Liu, W D]]
[[Category: Chen X]]
[[Category: Wu, Q Q]]
[[Category: Liu WD]]
[[Category: Zhang, H L]]
[[Category: Wu QQ]]
[[Category: Zhu, D M]]
[[Category: Zhang HL]]
[[Category: Biocatalyst]]
[[Category: Zhu DM]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Kred]]
[[Category: Oxidoreductase]]

Latest revision as of 09:41, 22 November 2023

Crystal structure of RasADH F12 from Ralstonia.sp in complex with NADPH and A6O

6ihh, resolution 1.80Å

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