6iq4: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 3: Line 3:
<StructureSection load='6iq4' size='340' side='right'caption='[[6iq4]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='6iq4' size='340' side='right'caption='[[6iq4]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6iq4]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IQ4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IQ4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6iq4]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IQ4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=D0X:[Ru(eta(6)-p-cymene)Cl-2(pta)'>D0X</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XIS:4-diphenylphosphanylbenzoic+acid'>XIS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iq4 OCA], [http://pdbe.org/6iq4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iq4 RCSB], [http://www.ebi.ac.uk/pdbsum/6iq4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iq4 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XIS:4-diphenylphosphanylbenzoic+acid'>XIS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iq4 OCA], [https://pdbe.org/6iq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iq4 RCSB], [https://www.ebi.ac.uk/pdbsum/6iq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iq4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>  Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> 
[https://www.uniprot.org/uniprot/H31_HUMAN H31_HUMAN]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 19:
</div>
</div>
<div class="pdbe-citations 6iq4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6iq4" style="background-color:#fffaf0;"></div>
==See Also==
*[[Histone 3D structures|Histone 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Adhireksan, Z]]
[[Category: Adhireksan Z]]
[[Category: Batchelor, L K]]
[[Category: Batchelor LK]]
[[Category: Davey, C A]]
[[Category: Davey CA]]
[[Category: DeFalco, L]]
[[Category: DeFalco L]]
[[Category: Dyson, P J]]
[[Category: Dyson PJ]]
[[Category: Anticancer]]
[[Category: Cross-link]]
[[Category: Dna binding protein-dna complex]]
[[Category: Gold]]
[[Category: Nucleosome]]
[[Category: Organometallic]]
[[Category: Ruthenium]]

Latest revision as of 13:16, 13 August 2026

Nucleosome core particle cross-linked with a hetero-binuclear molecule possessing RAPTA and gold(I) 4-(diphenylphosphino)benzoic acid groups.

6iq4, resolution 2.25Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=6iq4&oldid=4479579"