6ov1: Difference between revisions
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==Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity== | |||
<StructureSection load='6ov1' size='340' side='right'caption='[[6ov1]], [[Resolution|resolution]] 1.66Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ov1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OV1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ov1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ov1 OCA], [https://pdbe.org/6ov1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ov1 RCSB], [https://www.ebi.ac.uk/pdbsum/6ov1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ov1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RNPA_STAAU RNPA_STAAU] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | |||
==See Also== | |||
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Colquhoun J]] | |||
[[Category: Das C]] | |||
[[Category: Dunman P]] | |||
[[Category: Flaherty DP]] | |||
[[Category: Ha L]] | |||
[[Category: Noinaj N]] | |||
Latest revision as of 07:17, 11 October 2023
Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity
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