6tb5: Difference between revisions
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New page: '''Unreleased structure''' The entry 6tb5 is ON HOLD Authors: Description: Category: Unreleased Structures |
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The | ==The crystal structure of the DPS2 from DEINOCOCCUS RADIODURANS to 1.83A resolution (sequentially soaked in CaCl2 [5mM] for 20 min, then in Ammonium iron(II) sulfate [10mM] for 2h).== | ||
<StructureSection load='6tb5' size='340' side='right'caption='[[6tb5]], [[Resolution|resolution]] 1.83Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6tb5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TB5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tb5 OCA], [https://pdbe.org/6tb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tb5 RCSB], [https://www.ebi.ac.uk/pdbsum/6tb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tb5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DPS2_DEIRA DPS2_DEIRA] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). | |||
==See Also== | |||
*[[Ferritin 3D structures|Ferritin 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Deinococcus radiodurans]] | |||
[[Category: Large Structures]] | |||
[[Category: Cuypers MG]] | |||
[[Category: McSweeney S]] | |||
[[Category: Mitchell EP]] | |||
[[Category: Romao CV]] | |||
Latest revision as of 12:58, 24 January 2024
The crystal structure of the DPS2 from DEINOCOCCUS RADIODURANS to 1.83A resolution (sequentially soaked in CaCl2 [5mM] for 20 min, then in Ammonium iron(II) sulfate [10mM] for 2h).
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